I know what you are running and you are fine. I am still going over things and the only thing I am convinced of at thai point is the GTX 680 ( Newegg stays sold out on those things ). I think I can get 3.0 PCIe support with a BiOS upgrade on this MOBO, but not sure as I am still looking into that. With the Z77, you get 4 USB 3.0 ports instead of the 2 that I have with the Z68 board. One upside to the IGP on the Ivy Bridge ( HD4000 for the 3750k ) it supports DX11 whereas the Sandy supported DX10.1.
The other thing, is that the Ivy Bridge supports native OpenCL on the GPU, instead of being hacked up and running on the CPU.